AU

AutoGen

19,500PythonMulti-Agent

Microsoft's next-gen agent framework for building multi-agent conversations.

PythonMicrosoftMulti-Agent

Overview

AutoGen is a Microsoft research project that provides a framework for building multi-agent conversation systems. It enables developers to create agents that can converse with each other to solve tasks, with built-in support for human-in-the-loop interactions.

Features

  • Conversation-centric programming
  • Human-in-the-loop support
  • Code execution agents
  • Group chat management
  • Customizable agent behaviors

Installation

pip install pyautogen

Pros

  • +Backed by Microsoft research
  • +Excellent for complex problem solving
  • +Strong code execution capabilities
  • +Active research community

Cons

  • Steeper learning curve
  • Documentation can be scattered
  • API changes frequently

Alternatives

Documentation

AutoGen Documentation

Introduction

AutoGen is a Microsoft research project that provides a framework for building multi-agent conversation systems. It enables developers to create sophisticated AI applications through natural agent-to-agent conversations.

Installation

pip install pyautogen

Quick Start

Define Your Agents

from autogen import AssistantAgent, UserProxyAgent

assistant = AssistantAgent(
    name="assistant",
    system_message="You are a helpful assistant.",
)

user_proxy = UserProxyAgent(
    name="user_proxy",
    code_execution_config={"work_dir": "coding", "use_docker": False},
    human_input_mode="NEVER",
)

Start a Conversation

user_proxy.initiate_chat(
    assistant,
    message="Write and run Python code to print 'Hello World'",
)

Conversation Patterns

Two-Agent Conversation

user_proxy.initiate_chat(assistant, message="...")

Group Chat

from autogen import GroupChat, GroupChatManager

group_chat = GroupChat(agents=[assistant, user_proxy], messages=[])
manager = GroupChatManager(groupchat=group_chat)
user_proxy.initiate_chat(manager, message="...")

Code Execution

AutoGen can automatically write and execute code:

assistant = AssistantAgent(
    name="assistant",
    llm_config={"config_list": config_list},
)

user_proxy = UserProxyAgent(
    name="user_proxy",
    code_execution_config={"work_dir": "coding", "use_docker": False},
)

user_proxy.initiate_chat(
    assistant,
    message="Plot a chart of NVDA and TESLA stock price change YTD",
)

Human-in-the-Loop

user_proxy = UserProxyAgent(
    name="user_proxy",
    human_input_mode="ALWAYS",  # Always ask for human input
)

Use Cases

AutoGen excels in scenarios requiring natural multi-agent conversations and emergent behavior:

Use CaseWhy AutoGen
Multi-Agent ResearchAgents debate and refine answers through conversation
Code Generation & ReviewAssistant writes code, reviewer critiques, iterates
Creative CollaborationMultiple agents brainstorm and iterate on ideas
Customer Service TeamsTriage → Specialist → Resolution agents in conversation
Educational TutorsMultiple tutor agents with different teaching styles

Pros & Cons

✅ Pros

  • Natural conversation model — Intuitive for building conversational systems
  • Low barrier to entry — Simple API, easy to get started
  • Built-in code execution — Agents can write and run code automatically
  • Human proxy pattern — Humans participate naturally in conversations
  • Group chat support — Multi-agent discussions with automatic speaker selection
  • Emergent behavior — Let agents figure out the best approach collaboratively
  • Microsoft backing — Active development, good documentation, enterprise support
  • Flexible termination — Custom termination messages and conditions

❌ Cons

  • Implicit state — Conversation history is the state, less explicit than LangGraph
  • Limited persistence — No built-in checkpointing for long-running workflows
  • Less control over flow — Emergent behavior can be unpredictable
  • No streaming optimization — Streaming support is basic compared to LangGraph
  • Python-centric — Primary focus on Python (JS support is limited)
  • Can be slow — Multi-turn conversations can be expensive with LLM calls

Comparison with Alternatives

FeatureAutoGenLangGraphCrewAI
ParadigmConversation-centricStateful graphsRole-based teams
StateImplicit (messages)Explicit TypedDictImplicit (messages)
Control FlowImplicit via conversationExplicit edgesSequential/hierarchical
Human-in-the-loopBuilt-in (human proxy)Advanced (interrupt)Basic
Code executionBuilt-inVia toolsVia tools
Learning curveLowMedium-HighLow-Medium
Best forConversations, prototypingProduction workflowsContent pipelines

Real-World Examples

Example 1: Code Generation with Review

from autogen import AssistantAgent, UserProxyAgent

# Code writer agent
coder = AssistantAgent(
    name="coder",
    system_message="You are an expert Python programmer. Write clean, efficient code.",
    llm_config={"config_list": [{"model": "gpt-4", "api_key": "YOUR_KEY"}]},
)

# Code reviewer agent
reviewer = AssistantAgent(
    name="reviewer",
    system_message="You are a senior code reviewer. Check for bugs, security issues, and best practices.",
    llm_config={"config_list": [{"model": "gpt-4", "api_key": "YOUR_KEY"}]},
)

# User proxy for human input
user_proxy = UserProxyAgent(
    name="user",
    human_input_mode="TERMINATE",  # Ask until TERMINATE message
    code_execution_config={"work_dir": "coding", "use_docker": False},
)

# Start a conversation with the reviewer involved
user_proxy.initiate_chat(
    coder,
    message="Write a Python function to calculate the Fibonacci sequence",
    max_turns=5,
)

Example 2: Research Team with Group Chat

from autogen import AssistantAgent, GroupChat, GroupChatManager

# Specialized agents
researcher = AssistantAgent(
    name="researcher",
    system_message="You are a research specialist. Find and summarize relevant information.",
)

analyst = AssistantAgent(
    name="analyst",
    system_message="You are a data analyst. Analyze trends and draw insights.",
)

writer = AssistantAgent(
    name="writer",
    system_message="You are a technical writer. Transform research into clear articles.",
)

# Create group chat
groupchat = GroupChat(
    agents=[researcher, analyst, writer],
    messages=[],
    max_round=12,
    speaker_selection_method="auto",  # Auto-select next speaker
)

manager = GroupChatManager(
    groupchat=groupchat,
    llm_config={"config_list": [{"model": "gpt-4", "api_key": "YOUR_KEY"}]},
)

# Start the conversation
user_proxy.initiate_chat(
    manager,
    message="Research and write about the latest developments in AI agents",
)

Best Practices

  1. Use clear system messages — Guide agent behavior effectively with detailed instructions.
  2. Leverage code execution — Let agents write and test code for validation.
  3. Use human-in-the-loop — For critical decisions, set human_input_mode="TERMINATE".
  4. Start simple — Begin with two-agent conversations, then scale to groups.
  5. Set max_turns — Prevent infinite conversation loops.
  6. Use termination messages — Define clear "TERMINATE" conditions.
  7. Custom speaker selection — For group chats, consider speaker_selection_method.

Troubleshooting

IssueSolution
Infinite loopsSet max_turns and clear termination messages
Agent not respondingCheck LLM config and API key validity
Code execution failsVerify work_dir exists and has write permissions
Group chat not workingEnsure all agents have llm_config set
Poor output qualityImprove system messages with more context

Resources


Last updated: June 2026